Lymphocytic Choriomeningitis

Viral Diseases

Animals Involved

Reservoir mainly house mouse; can be maintained in some other mice, hamster populations; also infects guinea pigs, chinchillas, rats, nonhuman primates, some other mammals

Known Distributions

Worldwide

Probable Means of Spreading

Contact with host excretions and secretions; bites; possibly ingestion

Clinical Manifestations in People

Ranges from mild flu­like illness to biphasic with meningitis in second phase; complications (eg, arthritis, parotitis, orchitis) possible; can cause congenital defects (CNS defects, chorioretinitis, and other ocular lesions) or abortion; rarely fatal in immunocompetent (overall case fatality rate <1%)

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