Lassa Fever

Viral Diseases

Animals Involved

Wild rodents, usually multimammate mouse

Known Distributions

West Africa

Probable Means of Spreading

Contact with rodent excretions, secretions, or tissues; aerosols

Clinical Manifestations in People

Gradual onset of nonspecific febrile illness, may be followed by chest pain, cough, GI signs, hepatitis; severe swelling of head and neck, hypotension/shock can develop; pleural/pericardial effusions; hemorrhagic syndrome less common; overall mortality rate 1% in endemic areas; case fatality rate 20% among hospitalized patients

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