Herpes B Virus Disease

Viral Diseases

Animals Involved

Carried in genus Macaca (Old World macaques), with lifelong latency and potential for periodic shedding after infection; other nonhuman primates susceptible; cell cultures

Known Distributions

Worldwide, can be common, especially in closed groups of macaques; human cases rare

Probable Means of Spreading

Monkey bites and scratches, contamination of mucous membranes with infected saliva, secretions

Clinical Manifestations in People

Influenza­like symptoms; vesicular skin lesions, pain, or itching around wound, followed by severe encephalitis with seizures, paralysis, coma; 85% mortality rate

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