Hantavirus Pulmonary Syndrome (HPS)

Viral Diseases

Animals Involved

Rodents; each virus tends to be associated with a single reservoir host

Known Distributions

North and South America

Probable Means of Spreading

Aerosols from rodent excretions and secretions; contact with broken skin and mucous membranes; rodent bites

Clinical Manifestations in People

Prodromal stage with nonspecific febrile illness; followed by respiratory failure, cardiac abnormalities; hemorrhagic signs possible with South American viruses; significant kidney disease uncommon; mortality rate varies with the virus, but can reach 40%–60%

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