Murine typhus; Fleaborne typhus

Rickettsial Diseases

Animals Involved

Rats are major reservoir; cats, opossums, possibly dogs, other species in peridomestic cycle

Known Distributions

Worldwide, especially warmer regions

Probable Means of Spreading

Infected rodent fleas, usually via flea feces; cat fleas seem to be involved in some cycles

Clinical Manifestations in People

Fever, severe headache, central rash (not always observed); other signs, including arthralgia, cough, nausea/vomiting in some; mortality rate 4% without treatment

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Rickettsial Diseases