Mediterranean spotted fever; Boutonneuse fever; Tick bite fever;

Rickettsial Diseases

Animals Involved

Dogs, rabbits implicated as reservoirs; other animals can be infected

Known Distributions

Europe, especially Mediterranean; cases reported in sub­Saharan Africa

Probable Means of Spreading

Bite of infected ticks (mainly Rhipicephalus sanguineus, also others), crushing tick

Clinical Manifestations in People

Nonspecific febrile illness; eschar (typically single) may or may not be present; rash, often maculopapular, in most; life­threatening disseminated disease or neurologic signs possible but uncommon; case fatality rate 1%–3% if untreated

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See Also:

African tick bite fever

Rickettsial Diseases