Variant Creutzfeldt­ Jakob Disease

Prion Diseases

Animals Involved

Cattle are most important host; also infects other ruminants, cats and other felids, lemurs

Known Distributions

Most cases in the UK but also in many other countries

Probable Means of Spreading

Ingestion of bovine products, especially those contaminated with CNS tissues

Clinical Manifestations in People

Neurodegenerative disorder similar to sporadic Creutzfeldt­Jakob disease but often in younger patients and progresses more rapidly; always fatal

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