Animals Involved
Old and New World monkeys, apes
Known Distributions
P knowlesi in Asia; other species exist in Central and South America, Asia, Africa
Probable Means of Spreading
Bite of anopheline mosquitoes
Clinical Manifestations in People
Febrile episodes with chills; headache, myalgia, malaise, cough, nausea, vomiting, and other symptoms in some; cases range from mild, selflimiting to fatal (3% case fatality rate for P knowlesi)